Mother Jones (one of my favorite publications) had a short Q&A with Dan Walsh, creator of Garfield Minus Garfield (one of my favorite niche websites).
So, was I onto something with my whole theory that Garfield Minus Garfield is about identification with the "product" in a fractured late capitalist society, or was I full of crap?
Yeah I think you were on to something. It's Jon's inability to "fit in." It's about being a sad, bored, lonely nerd on a Saturday night. I can't imagine why it became so successful on the internet ;-)
Read more here.